Protein G SepFast Large Bead Immunoaffinity Resin

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Protein G SepFast Large Bead has a particle size of 150 – 350 µm, particularly good for processing viscous or cell-containing feedstocks (i.e. high settling rate and extremely low column pressure).

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Description

Protein G SepFast Large Bead has a particle size of 150 – 350 µm, particularly good for processing viscous or cell-containing feedstocks (i.e. high settling rate and extremely low column pressure).

Protein G SepFast is a family of affinity chromatography media for the purification of immunoglobulins and binds to the Fc region of IgG from a variety of mammalian species. Protein G SepFast may be used to isolate and purify classes, subclasses and fragments of immunoglobins from any biological fluid or cell culture medium. Protein G SepFast is extremely useful for isolation of immune complexes.

The potential applications of protein G include practically all of the current and projected applications of protein A. Protein G and protein A, however, have different IgG binding specificities, dependent on the origin of the IgG. Compared to protein A, protein G binds more strongly to polyclonal IgG, for example, from cow, sheep and horse. Furthermore, unlike protein A, protein G binds polyclonal rat IgG, human IgG3 and mouse IgG1.

Protein G SepFast Large Bead is developed and supported for production scale chromatography. We offer both loose medium and pre-packed ready-to-use disposable columns.

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